A Basetheme for Drupal, using YUI-grids as layout framework, using genesis.
Forked off Genesis (drupal.org project page)
More on YUI 3 here: http://developer.yahoo.com/yui/3/ More on YUI-grids here: http://developer.yahoo.com/yui/3/cssgrids/
NOTE: currently the stable active maintained YUI is version 3, which does not include a stable release of grids. Still, this unstable version is the one used here.